自1929年出版以來，這本雙月刊探討了一般生物化學的各個方面，包括對真核生物細胞和分子生物學實驗研究的最新報道，以及對當前感興趣的主題的評論文章和公認的國際專家的注釋。每年的特刊致力于擴大生物化學和細胞生物學的新研究領域。

Published since 1929, this bimonthly journal explores every aspect of general biochemistry and includes up-to-date coverage of experimental research into cellular and molecular biology in eukaryotes, as well as review articles on topics of current interest and notes contributed by recognized international experts. Special issues each year are dedicated to expanding new areas of research in biochemistry and cell biology.