該雜志及時發表與醫學研究相關的評論，廣泛定義了作者已作出重大貢獻的主題。適當的主題包括但不限于重要疾病和疾病載體的潛在病理生理學;各種疾病的治療方法;目的研究藥物分子靶點的性質。促進尋找治療方法的重要新方法;基因組學和蛋白質組學;藥物系列的構效關系開發新的成像和診斷工具;藥物代謝;藥物輸送;化學藥物的藥代動力學、藥效學和臨床特點的重要性。評論主要由編輯征求意見;不過，也鼓勵自愿捐款。在后一種情況下，潛在的作者被要求在開始寫作前與合作編輯中的任何一位聯系提綱，以避免重復工作，并確保主題及其報道水平的適宜性。

The journal publishes timely critical reviews of topics related to medicinal research broadly defined to which the authors have made significant contributions. Appropriate topics include but are not limited to the underlying pathophysiology of important diseases and disease vectors; therapeutic approaches to the treatment of various diseases; the properties of molecular targets for therapeutic agents; important new methodologies facilitating the search for therapies; genomics and proteomics; structure-activity correlations of drug series; the development of new imaging and diagnostic tools; drug metabolism; drug delivery; chemical pharmacological pharmacokinetic pharmacodynamic and clinical characteristics of importance. Reviews are mainly solicited by the editors; however voluntary contributions are also encouraged. In the latter case potential authors are asked to contact either co-editor with an outline before beginning to write in order to avoid duplication of effort and to ensure suitability of the topic and its level of coverage.