《公共科學圖書館·生物學》收錄了在從分子到生態系統的所有生物科學領域中具有特殊意義、獨創性和相關性的著作，包括化學、醫學和數學等其他學科交叉領域的著作。我們也歡迎數據驅動的元研究文章，這些文章評估并旨在提高生命科學和其他領域的研究標準。我們的聽眾是國際科學界以及世界各地的教育工作者、決策者、患者倡導團體和感興趣的公眾成員。

PLOS Biology features works of exceptional significance, originality, and relevance in all areas of biological science, from molecules to ecosystems, including works at the interface of other disciplines, such as chemistry, medicine, and mathematics. We also welcome data-driven meta-research articles that evaluate and aim to improve the standards of research in the life sciences and beyond. Our audience is the international scientific community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world.